Charles Tritt, Ph.D.

Ph.D.

Chemical Engineering

Ohio State University

1994

M.S.

Biomedical Engineering

Ohio State University

1986

B.S.

Chemical Engineering

Ohio State University

1982

"Honored Guest" (speaker)

2007
ICAS Convocation Ceremony, Manipal University, Manipal, India

Alumni Research Award

Ohio State University

Falk Engineering Education Award

MSOE, 1995

Human-Human Interface

DefCon 25, Los Vegas, NV, 2017  

Introduction to Arduino Embedded Systems and Their Use with Matlab

Department of Electrical and Electronics Engineering, Manipal Institute of Technology, Manipal, India, 2015  

Collaboration Opportunities with MSOE’s Biomedical Engineering Program

CTS Thursday Noon Conference, Medical College of Wisconsin, Milwaukee, 2015  

Board 19: Work in Progress: Spicing Up Instruction of Professional Topics in Biomedical Engineering

LaMack, J.A., Imas, O., Larry Fennigkoh, P.E., Tritt, C.S., Dos Santos, I.

2018

Practical knowledge of topics such as FDA and international regulatory compliance, standards for medical devices, quality control in medical device manufacturing, and healthcare economics, are among the distinguishing skills of many biomedical engineers. Furthermore, industry highly values familiarity with these topics in BME undergraduates. However, it is challenging to instruct students on these inherently dry topics, particularly in the absence of practical applications. Previous approaches toward teaching these topics in our curriculum mainly involved lectures scattered throughout our extended capstone design course series. While the coupling between presentation of these topics and students’ design projects was often successful, student feedback was mixed in response to this approach. Students sometimes reported that presentations covering these topics were not timely (different design projects progress at different paces and address the topics at different points in time), that they were a distraction from the main goal of conducting design work in the laboratory, or that they were simply boring.

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Design of Artificial Red Blood Cells using Polymeric Hydrogel Microcapsules: Hydrogel Stability Improvement and Polymer Selection

Zhang, W., Bissen, M.J., Savela, E.S., Clausen, J.N., Fredricks, S.J., Guo, X., Paquin, Z.R., Dohn, R.P., Pavelich, I.J., Polovchak, A.L., Wedemeyer, M.J.

2016

It was observed that the molecular weight of the cross-linker oligochiotsan had no significant improvement on microcapsule stability. On the other hand, the treatment of pectin-oligochitosan microcapsules with Ca2+ increased the microcapsule stability significantly. Different types of alginate were used; however, no red-blood-cell-shaped microcapsules could be produced, which is likely due to the charge-density difference between deprotonated pectin and alginate polymers.

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Novel pectin-based carriers for colonic drug delivery

Zhang, W., Mahuta, K.M., Mikulski, B.A., Harvestine, J.N., Crouse, J.Z., Lee, J.C., Kaltchev, M.G., Tritt, C.S.

2016

Pectin-based hydrogel carriers have been studied and shown to have promising applications for drug delivery to the lower GI tract, especially to the colonic region. However, making sure these hydrogel carriers can pass through the upper GI tract and reach the targeted regions, after oral administration, still remains a challenge to overcome. A solution to this problem is to promote stronger cross-linking interactions within the pectin-based hydrogel network. The combined usage of a divalent cation (Ca2+) and the cationic biopolymer oligochitosan has shown to improve the stability of pectin-based hydrogel systems – suggesting that these two cross-linkers may be used to eventually help improve pectin-based hydrogel systems for colonic drug delivery methods.

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